Sanford’s brown lemur occurs in tropical moist and dry lowland and montane forests up to elevations of 1,400 m. It has been studied in the Ankarana Special Reserve and in Montagne d’Ambre National Park. In Ankarana, it appears to favor secondary forest, and is active both day and night (Wilson et al., 1988, 1989; Fowler et al., 1989; Freed, 1996). Groups are typically multi-male/multi-female. In Ankarana they may include up to 15 animals (Wilson et al., 1989), significantly larger than those observed in Montagne d’Ambre, which range from three to nine animals (Freed, 1996). At Montagne d’Ambre, overlapping home ranges of close to 15 ha have been reported (Arbelot-Tracqui, 1983). In Analamerana, a population density of 3.5–5.4 individuals/km2 has been reported by Banks (2005). Mating occurs in late May, and births usually take place in late September or early October after a gestation of about 120 days. There is no evidence of female dominance. The diet of Sanford’s brown lemur consists primarily of fruit, but includes other plant parts (buds, young leaves, flowers) according to seasonal availability, and also the occasional invertebrate (e.g., centipedes, millipedes and spiders). Flowers make up a greater portion of the diet during dry season months than they do during the rainy season (Freed, 1996). Eulemur sanfordi is also reported to associate with E. coronatus during the wet season, a time of greater food availability (Freed, 1996).