Avahi betsileo has a head-body length of 26–31.1 cm, a tail of 28.3–34.4 cm, a total length of 48–58.9 cm, and a weight of 900–1,200 g (Andriantompohavana et al., 2007; Lei et al., 2008). It differs significantly from other eastern woolly lemurs in having primarily light reddish-brown pelage on the upper body and on the dorsal surface of the extremities, with an underside that is dark gray towards the midline and diffusing to a light gray ventrolaterally. The tail is mainly reddish-brown and darker on the dorsal surface than on the ventral portion, which is a lighter reddish-blonde. There is a distinct facial mask, with grayish pelage under the mandible and diffuse, cream-colored eyebrow markings. The fur is thicker on the head than in other eastern Avahi, giving it a more rounded or oval-like apprearance (Andriantompohavana et al., 2007).
As of 2010, this species had not been studied in the wild.
East-central Madagascar. This species is currently known only from the Bemosary Classified Forest (Fandriana), though the limits of the distribution may ultimately prove to extend from the Mangoro River in the north to the Mananjary River in the south (Andriantompohavana et al., 2007).
Very little is known of the Betsileo woolly lemur, so the 2008 IUCN Red List classified it as Data Deficient (DD). It is not known to occur in any protected areas.
As of 2010, this species was not being kept in captivity (I. J. Porton, pers. comm.).
At the present time the only place where one can be sure of seeing this species is in the Bemosary Classified Forest, a forest fragment located about one hour’s walk from the village of Fandriana.